Specifications
- Supplier
- Proteintech
- Catalog No
- KE00023
- Sku
- KE00023-480T
- Product Name
- Human FKBPL ELISA Kit
- Description
- FKBPL, also named as DIR1, NG7 and WISp39, has similarity to the immunophilin protein family, which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. It is thought to have a potential role in the induced radioresistance, probably by increasing the rate of DNA repair in cells exposed to X rays. Breast cancer cells stably overexpressing FKBPL became dependent on estrogen for their growth and were dramaticaly more sensitive to the antiestrogens Tamoxifen and Fulvestrant, whereas FKBPL knockdown reverses this phenotype. FKBPL is an estrogen-inducible gene that acts as a cochaperone in ERa/Hsp90 molecular complexes; furthermore, FKBPL levels may be both a prognostic indicator and determinant of response to endocrine therapy. This kit is used to quantify FKBPL level in vivo.
- Size
- 5*96T
- Image
- https://www.ptglab.com/products/pictures/kit-2 FKBPL.jpg
- Datasheet
- https://www.ptglab.com/Products/Pictures/pdf/Human-FKBPL-ELISA-Kit-KE00023-datasheet.pdf
- Application
- Sandwich ELISA
- Target Immunogen
- FKBPL
- Reactivity
- Human
- Storage
- All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions.
- Shipping
- Blue ice
- Sample Type
- Serum, Plasma
- Product Type
- ELISAKit
- Sensitivity
- 7.0 pg/mL
- Range
- 31.25-2000 pg/mL
Documentation
No documentation found.
Publications
No publications found.
