Specifications
- Supplier
- BT Lab
- Catalog No
- BT-MCA3471
- Product Name
- PDHA1 Monoclonal Antibody
- Description
- The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Size
- 50μL, 100μL
- Application
- WB, IHC, ICC, FCM
- Host
- Mouse
- Clone
- 4E12D6
- Clonality
- Monoclonal
- Isotype
- Mouse IgG2a
- Target Immunogen
- PDHA1
- Reactivity
- Human, Mouse, Rat
- Storage
- 4°C|-20°C for long term storage
- Format
- Purified antibody in PBS with 0.05% sodium azide
- Synonym
- PDHA, PDHAD, PHE1A, PDHCE1A
Documentation
No documentation found.
Publications
No publications found.
