Specifications
- Supplier
- BT Lab
- Catalog No
- BT-MCA3372
- Product Name
- HLA-DPB1 Monoclonal Antibody
- Description
- HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
- Size
- 50μL, 100μL
- Application
- IHC, FCM
- Host
- Mouse
- Clone
- 5C9F4
- Clonality
- Monoclonal
- Isotype
- Mouse IgG1
- Target Immunogen
- HLA-DPB1
- Reactivity
- Human, Rat
- Storage
- 4°C|-20°C for long term storage
- Format
- Purified antibody in PBS with 0.05% sodium azide
- Synonym
- DPB1, HLA-DP, HLA-DPB, HLA-DP1B
Documentation
No documentation found.
Publications
No publications found.
