BT-MCA3117TCF7 Monoclonal Antibody

Article No
Size: 50μL, 100μL
Shipping Information: Room Temperature
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Specifications

Supplier: BT Lab
Catalog No: BT-MCA3117
Product Name: TCF7 Monoclonal Antibody
Description: This gene encodes a member of the T-cell factor/lymphoid enhancer-binding factor family of high mobility group (HMG) box transcriptional activators. This gene is expressed predominantly in T-cells and plays a critical role in natural killer cell and innate lymphoid cell development. The encoded protein forms a complex with beta-catenin and activates transcription through a Wnt/beta-catenin signaling pathway. Mice with a knockout of this gene are viable and fertile, but display a block in T-lymphocyte differentiation. Alternative splicing results in multiple transcript variants. Naturally-occurring isoforms lacking the N-terminal beta-catenin interaction domain may act as dominant negative regulators of Wnt signaling.
Size: 50μL, 100μL
Application: IHC, ICC, FCM
Host: Mouse
Clone: 1B4E9
Clonality: Monoclonal
Isotype: Mouse IgG1
Target Immunogen: TCF7
Reactivity: Human
Storage: 4°C|-20°C for long term storage
Format: Purified antibody in PBS with 0.05% sodium azide
Synonym: TCF-1

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