Specifications
- Supplier
- MedChemExpress
- Catalog No
- HY-100012
- Product Name
- CBR-5884
- Description
- CBR-5884 is an active, selective inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 33 μM. CBR-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with high serine biosynthetic activity. CBR-5884 selectively inhibits the proliferation of melanoma and breast cancer lines that have a high propensity for serine synthesis[1].
- Size
- 25 mg
- Datasheet
- http://file.medchemexpress.com/batch_PDF/HY-100012/CBR-5884-DataSheet-MedChemExpress.pdf
- Msds
- http://file.medchemexpress.com/batch_PDF/HY-100012/CBR-5884-SDS-MedChemExpress.pdf
- Application
- Cancer-programmed cell death
- Cas No
- 681159-27-3
- Target Immunogen
- Phosphoglycerate Dehydrogenase (PHGDH)
- Storage
- -20°C, 3 years; 4°C, 2 years (Powder)
- Shipping
- Room Temperature
- Product Type
- Reference compound
- Research Area
- Cancer
- Format
- C14H12N2O4S2
Documentation
No documentation found.
Publications
No publications found.
