Specifications
- Supplier
- Exalpha
- Product Name
- Mouse anti Human CD8 FITC - CD28 PE
- Description
- Identification of human cytotoxic/suppressor T cells expressing the 32 and 43,000 M.W. surface antigen. CD38 antigen is an integral membrane glycoprotein, M.W. 45 kD. Anti-human CD28 binds the 44kDa MW cell surface protein on the surface of most T cells. CD28 acts as the ligand for the B7/BB-1 molecule on the surface of activated B cells. B7/BB-1 co-stimulates T cells through CD28, along with CD2 and CD3. CD28 antigen is a disulfide-linked homodimeric glycoprotein. The CD28 antigen is present on approximately 60%-80% T lymphocytes (95% of CD4 and 50% of CD8 lymphocytes). CD28 regulates the expression of cytokines by T cells, not only IL-2, but also IL-1 alpha and CSF-1, usually synthesized by accessory cells. CD28 functions as a cell adhesion molecule (CAM) for certain T cell subsets.
- Size
- 50 Tests
- Application
- Flow Cytometry
- Host
- Mouse
- Isotype
- IgG1 (F)/IgG1 (PE)
- Target Immunogen
- CD8=Derived from the hybridization of mouse NS-1 myeloma cells with spleen cells from BALB/c mice immunized with human perherial blood T lymphocytes.CD28=Derived from the hybridization of mouse Sp2/O-Ag14 myeloma cells with spleen cells of BALB/c mice immunized with the HPB-ALL T-cell line.
- Storage
- Product should be stored at 4-8ºC. DO NOT FREEZE
- Shipping
- Room Temperature
- Product Type
- Primary antibodies
- Purification
- Protein A/G Chromatography
- Concentration
- Titered for flow cytometry
- Synonym
- CD8 FITC - CD28 PE
Documentation
No documentation found.
Publications
No publications found.
