Specifications
- Supplier
- Exalpha
- Product Name
- Mouse anti Human CD44
- Description
- CD44 is a 90-kD (GP90), collagen-binding, membrane glycoprotein, termed extracellular matrix receptor III (ECMR III), that is homologous to the lymphocyte homing receptor and CD44 antigen. CD44 is abundantly expressed in many epithelial tissues, and is localized predominantly to filopodia in cultured keratinocytes. CD44 is a polymorphic family of related membrane proteoglycans and glycoproteins possessing extensive diversity in both glycosylation and core protein sequence. Human neonatal foreskin keratinocytes (HFKs) and QG56 lung squamous carcinoma cells express an alternatively spliced form of the CD44 core protein (termed CD44E) that contains an additional 132 amino acids in the carbohydrate attachment region of the extracellular domain. HFKs, HT1080 fibrosarcoma and QG56 cells, as well as many other human cells, contain varying ratios of GP90. Differences in mass are due primarily to variation in carbohydrate moieties, including sulfated asparginelinked glycopeptides (GP), chondroitin sulfate (CS), and heparan sulfate (HS) glycosaminoglycans, as well as O-linked mucin and polylactosamine structure(s).
- Size
- 100 µg
- Application
- Flow Cytometry
- Host
- Mouse
- Clone
- 7F1
- Isotype
- IgG1
- Target Immunogen
- CD44=Derived from the hybridization of mouse Sp2/0 myeloma cells with spleen cells from BALB/c mice immunized with TCR-gamma epsilon thymocytes
- Storage
- Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles
- Shipping
- Room Temperature
- Product Type
- Primary antibodies
- Purification
- Protein A/G Chromatography
- Concentration
- See vial for concentration
- Synonym
- CD44
Documentation
No documentation found.
Publications
No publications found.
