Specifications
- Supplier
- Exalpha
- Product Name
- Mouse anti Human CD28
- Description
- Anti-human CD28 binds the 44kDa MW cell surface protein on the surface of most T cells. CD28 acts as the ligand for the B7/BB-1 molecule on the surface of activated B cells. B7/BB-1 costimulates T cells through CD28, along with CD2 and CD3.CD28 antigen is a disulfide-linked homodimeric glycoprotein. The CD28 antigen is present on approximately 60%-80% T lymphocytes (95% of CD4 and 50% of CD8 lymphocytes). CD28 regulates the expression of cytokines by T cells, not only IL-2, but also IL-1 alpha and CSF-1, usually synthesized by accessory cells. CD28 functions as a cell adhesion molecule (CAM) for certain T cell subsets.
- Size
- 100 µg
- Application
- Flow Cytometry
- Host
- Mouse
- Clone
- B-23
- Isotype
- IgG1
- Storage
- Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles
- Shipping
- Ship at ambient temperature
- Product Type
- Primary antibodies
- Purification
- Protein A/G Chromatography
- Concentration
- See vial for concentration
- Source
- Derived from the hybridization of mouse Sp2/O-Ag14 myeloma cells with spleen cells of BALB/c mice immunized with the HPB-ALL T-cell line.
- Synonym
- CD28
Documentation
No documentation found.
Publications
No publications found.
