Specifications
- Supplier
- BT Lab
- Catalog No
- BT-MCA2085
- Product Name
- MCM3 Monoclonal Antibody
- Description
- The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Several transcript variants encoding different isoforms have been found for this gene.
- Size
- 50μL, 100μL
- Application
- WB, IHC, ICC, FCM
- Host
- Mouse
- Clone
- 1D4A3
- Clonality
- Monoclonal
- Isotype
- Mouse IgG1
- Target Immunogen
- MCM3
- Reactivity
- Human, Monkey, Rat
- Storage
- 4°C|-20°C for long term storage
- Format
- Purified antibody in PBS with 0.05% sodium azide
- Synonym
- HCC5, P1.h, RLFB, P1-MCM3
Documentation
No documentation found.
Publications
No publications found.
